Vicenza Cathedral (Cattedrale di Santa Maria Annunziata, Duomo di Vicenza) is a Roman Catholic cathedral. It is the seat of the Bishop of Vicenza, and is dedicated to the Annunciation of the Virgin Mary.
Construction of the cathedral was begun in 1482, to plans by Lorenzo of Bologna, and completed in the 1560s. The cupola was planned by Andrea Palladio and probably the north doorway also.
Only the original façade survived the bombing of World War II; the rest of the present building has been reconstructed.
The maestri di cappella include Fra Ruffino d'Assisi (1525-31), Nicola Vicentino (1563-65), Giammateo Asola and his pupil Leone Leoni (1588-1627).
The belltower has five bells in the chord of Eb; the oldest one was cast in the 17th century.