Palazzo Bordonaro is a 16th-century palace in Palermo, located in the Kalsa district.

The palace was built around the 16th century but underwent various transformations, first with the redefinition of the Cassaro and subsequently with the opening of the new road: Via Maqueda.

The main facade of the palace faces Piazza Pretoria. With the redefinition of the Cassaro, the facade facing it was rebuilt, while with the opening of Via Maqueda, one of the four corners was created on the corner of the palace.