San Sepolcro, which project was signed by Alessio Tramello, was built between 1513 and 1534 as commissioned by the Olivetani monks nearby the area where centuries before a church dedicated to Santo Sepolcro once stood. The façade nor the portal we can see today – certainly built later on – seem to be part of Tramello’s project.
During Napoleon’s dominion the church suspended all religious activities to be used as military hospital; only in 1903, thanks to the bishop Scalabrini, was reopened for religious purposes after dedicated renovation works. 

Next to the church there is the former convent of Padri Olivetani with two beautiful cloisters included in the spaces occupied by the Civil Hospital. 

Inside, the church is large and divided by pillars, it is characterized by a frescoed chiaroscuro decoration that runs like a ribbon above the arches in the naves. The presbytery houses sculptures by Paolo Perotti.