Attached to the theater, the museum was set up by the Memmo Foundation, in a classroom of the prestigious seventeenth-century palace that belonged to the Romano family.
The museum, in addition to containing artifacts from excavations carried out in the first half of the last century that brought to light the ancient monument, houses an exhibition entitled "Rome. The Scene of Life" created in collaboration with the Archaeological Superintendency of Rome and the Archaeological Superintendency of Puglia, which illustrates the theme of scenography and illusionistic representation in the Roman world.
The series of nine theatrical masks from Hadrian's Villa in Tivoli has a great scenic effect. Finally, thanks to a model, it is possible to see the reconstruction of a large urban area of Lupiae (ancient Lecce) in Roman imperial times.